By Jennie R. Lill,Wendy Sandoval
The definitive consultant to the myriad analytical recommendations to be had to scientists occupied with biotherapeutics research
Analytical Characterization of Biotherapeutics covers all present and rising analytical instruments and strategies used for the characterization of healing proteins and antigen reagents. From simple recombinant antigen and antibody characterization, to advanced analyses for more and more advanced molecular designs, the ebook explores the heritage of the research thoughts and provides precious insights into an important rising analytical strategies. moreover, it frames serious questions warranting consciousness within the layout and supply of a healing protein, exposes analytical demanding situations that can ensue whilst characterizing those molecules, and provides a couple of established suggestions.
The first single-volume consultant of its style, Analytical Characterization of Biotherapeutics brings jointly contributions from scientists on the cutting edge of biotherapeutics study and production. Key issues coated in-depth comprise the structural characterization of recombinant proteins and antibodies, antibody de novo sequencing, characterization of antibody drug conjugates, characterization of bi-specific or different hybrid molecules, characterization of producing host-cell contaminant proteins, analytical instruments for biologics molecular review, and more.
- Each bankruptcy is written by way of a well-known professional or specialists of their box who speak about present and leading edge methods to completely characterizing biotherapeutic proteins and antigen reagents
- Covers the complete variety of characterization thoughts for big molecule dependent therapeutics
- Provides an up to date account of the most recent ways used for big molecule characterization
- Chapters disguise the historical past had to comprehend the demanding situations to hand, recommendations to represent those huge molecules, and a precis of rising innovations for analytical characterization
Analytical Characterization of Biotherapeutics is an updated source for analytical scientists, biologists, and mass spectrometrists interested by the research of biomolecules, in addition to scientists hired within the prescription drugs and biotechnology industries. Graduate scholars in biology and analytical technological know-how, and their teachers will locate it to be interesting and instructive supplementary reading.
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