By Miguel A. Aon,Valdur Saks,Uwe Schlattner
Systems Biology represents a brand new paradigm aiming at a whole-organism-level realizing of organic phenomena, emphasizing interconnections and sensible interrelationships instead of part elements. The learn of community homes, and the way they regulate and control habit from the mobile to organism point, constitutes a first-rate concentration of platforms Biology. This ebook addresses from a unique viewpoint a huge unsolved organic challenge: realizing how a mobile works and what is going mistaken in pathology. the duty undertaken through the authors is in equivalent components conceptual and methodological, integrative and analytical, experimental and theoretical, qualitative and quantitative, didactic and complete. primarily, they resolve the spatio-temporal unfolding of interacting mass-energy and data networks on the mobile and organ degrees, in addition to its modulation via activation or repression by way of signaling networks to provide a definite phenotype or (patho)physiological reaction.
Starting with the historic roots, in 13 chapters this paintings explores the structures Biology of signaling networks, mobile constructions and fluxes, organ and microorganism services. In doing so, it establishes the root of a twenty first century method of organic complexity.
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